Escherichia coli of sequence type 3835 carrying blaNDM-1, blaCTX-M-15, blaCMY-42 and blaSHV-12

New Delhi metallo-β-lactamase (NDM) represents a serious challenge for treatment and public health. A carbapenem-resistant Escherichia coli clinical strain WCHEC13-8 was subjected to antimicrobial susceptibility tests, whole genome sequencing and conjugation experiments. It was resistant to imipenem (MIC, >256 μg/ml) and meropenem (MIC, 128 μg/ml) and belonged to ST3835. blaNDM-1 was the only carbapenemase gene detected. Strain WCHEC13-8 also had a plasmid-borne AmpC gene (blaCMY-42) and two extended-spectrum β-lactamase genes (blaCTX-M-15 and blaSHV-12). blaNDM-1 and blaSHV-12 were carried by a 54-kb IncX3 self-transmissible plasmid, which is identical to plasmid pNDM-HF727 from Enterobacter cloacae. blaCMY-42 was carried by a 64-kb IncI1 plasmid and blaCTX-M-15 was located on a 141-kb plasmid with multiple F replicons (replicon type: F36:A4:B1). blaCMY-42 was in a complicated context and the mobilisation of blaCMY-42 was due to the transposition of IS Ecp1 by misidentifying its right-end boundary. Genetic context of blaNDM-1 in strain WCHEC13-8 was closely related to those on IncX3 plasmids in various Enterobacteriaceae species in China. In conclusion, a multidrug-resistant ST3835 E. coli clinical strain carrying blaNDM-1, blaCTX-M-15, blaCMY-42 and blaSHV-12 was identified. IncX3 plasmids may be making a significant contribution to the dissemination of blaNDM among Enterobacteriaceae in China

Temporal and Spectral Correlations of Cyg X-1

Temporal and spectral properties of X-ray rapid variability of Cyg X-1 are studied by an approach of correlation analysis in the time domain on different time scales. The correlation coefficients between the total intensity in 2-60 keV and the hardness ratio of 13-60 keV to 2-6 keV band on the time scale of about 1 ms are always negative in all states. For soft states, the correlation coefficients are positive on all the time scales from about 0.01 s to 100 s, which is significantly different with that for transition and low states. Temporal structures in high energy band are narrower than that in low energy band in quite a few cases. The delay of high energy photons relative to low energy ones in the X-ray variations has also been revealed by the correlation analysis. The implication of observed temporal and spectral characteristics to the production region and mechanism of Cyg X-1 X-ray variations is discussed.Comment: 17 pages, 6 figures included, to appear in Ap

Equilibrium states of the pressure function for products of matrices

Let $\{M_i\}_{i=1}^\ell$ be a non-trivial family of $d\times d$ complex matrices, in the sense that for any $n\in \N$, there exists $i_1... i_n\in \{1,..., \ell\}^n$ such that $M_{i_1}... M_{i_n}\neq {\bf 0}$. Let $P \colon (0,\infty)\to \R$ be the pressure function of $\{M_i\}_{i=1}^\ell$. We show that for each $q>0$, there are at most $d$ ergodic $q$-equilibrium states of $P$, and each of them satisfies certain Gibbs property.Comment: 12 pages. To appear in DCD

Microwave-mediated heat transport through a quantum dot

The thermoelectric effect in a quantum dot (QD) attached to two leads in the presence of microwave fields is studied by using the Keldysh nonequilibrium Green function technique. When the microwave is applied only on the QD and in the linear-response regime, the main peaks in the thermoelectric figure of merit and the thermopower are found to decrease, with the emergence of a set of photon-induced peaks. Under this condition the microwave field can not generate heat current or electrical bias voltage. Surprisingly, when the microwave field is applied only to one (bright) lead and not to the other (dark) lead or the QD, heat flows mostly from the dark to the bright lead, almost irrespectively to the direction of the thermal gradient. We attribute this effect to microwave-induced opening of additional transport channels below the Fermi energy. The microwave field can change both the magnitude and the sign of the electrical bias voltage induced by the temperature gradient.Comment: 5 figur

Structural, optical, magnetic and electrical properties of Zn1-x Co (x) O thin films

Despite a considerable effort aiming at elucidating the nature of ferromagnetism in ZnO-based magnetic semiconductor, its origin still remains debatable. Although the observation of above room temperature ferromagnetism has been reported frequently in the literature by magnetometry measurement, so far there has been no report on correlated ferromagnetism in magnetic, optical and electrical measurements. In this paper, we investigate systematically the structural, optical, magnetic and electrical properties of Zn1-x Co (x) O:Al thin films prepared by sputtering with x ranging from 0 to 0.33. We show that correlated ferromagnetism is present only in samples with x > 0.25. In contrast, samples with x < 0.2 exhibit weak ferromagnetism only in magnetometry measurement which is absent in optical and electrical measurements. We demonstrate, by systematic electrical transport studies that carrier localization indeed occurs below 20-50 K for samples with x < 0.2; however, this does not lead to the formation of ferromagnetic phase in these samples with an electron concentration in the range of 6 x 10(19) cm(-3) 1 x 10(20) cm(-3). Detailed structural and optical transmission spectroscopy analyses revealed that the anomalous Hall effect observed in samples with x > 0.25 is due to the formation of secondary phases and Co clusters.Comment: 28 pages, 8 figure